Alternatively, 18.75 mg twice daily. The usual adult dose is one tablet (37.5 mg) daily, as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. % These include, but are not limited to:Whether the care and treatment of obese patients and weight management is new to the APRNs existing practice, and whether this aspect of practice is within the APRNs national certification and patient population specialty, meeting the scope of practice requirements in Section 4723.43, ORC. Specializes in Med-Surg, Trauma, Ortho, Neuro, Cardiac. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. NDC 42806-810-01 In patients with severe renal impairment (eGFR 15 to 29 mL/min/1.73m2), limit the dosage of Phentermine to 15 mg daily [see Dosage and Administration (2.2)]. = Drug information provided by: IBM Micromedex. potentially hazardous activities such as operating machinery or driving FULL PRESCRIBING INFORMATION in the presence of other risk factors (e.g., controlled hypertension, 333-33-100411 Tasks 35 Common side effects of phentermine include: Phentermine is one of the most prescribed weight-loss medicines. Fatigue and depression usually follow the central stimulation. See DrugAbuse and Dependence (9.3). Each brand has its own way of manufacturing the drug and, in some cases, combines it with other chemicals to make it more effective or to add additional features to its use. 4 It should also not be taken within 14 days after taking an MAO inhibitor. The combined drug is approved for long-term use. (5) A treatment plan based upon the clinical information obtained, to include all of the following components: (a) Diagnosis; (b) Objective goals for treatment; (c) Rationale for the medication choice and dosage; and (d) Planned duration of treatment and steps for further assessment and follow-up. Phentermine has been linked to many complications; knowing these details will help patients minimize their risk of experiencing such unwanted scenarios. Talk with your doctor before starting an exercise program. Dispense in a tight container as defined in the USP, with a child-resistant closure (as required). It can help weight loss by making you less hungry. The risks include, but are not limited to: See also, for example, Adverse Reactions (6) and Use in SpecificPopulations (8). Some patients need to take the drug an hour before they eat breakfast, while others are advised to take it approximately one to two hours after breakfast. Y$iqzZz\vlt1a;svw&aBS8Z(HGCkr&_Qxt97t,GWceTL^QqX(%8_A2'"%tD'DNz"G*"Tc. It's designed to help prevent opioid dependence for Ohio's injured workers through its three primary goals. Unfortunately, the answer is no in most cases. Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis. Available for Android and iOS devices. Phentermine also is offered combined with topiramate for weight loss (Qsymia). Accessed Oct. 11, 2022. Specializes in NICU, PICU, Transport, L&D, Hospice. ohio.gov under the Practice APRN link.Although the Formulary allows CTP holders to prescribe these three drugs under the circumstances documented by their respective standard care arrangement, there are other factors that must be considered by the CTP holder prior to initiating Qsymin, Belviq or Contrave prescriptions for patients. - 7 Unfortunately, patients experienced a variety of side effects, which included severe heart toxicity and hypertension. If obesity is impacting your fertility or reproductive health, or if you have a specific condition that affects weight (such as PCOS), your gynecologist may consider prescribing phentermine as a short-term weight management strategy. Before starting with consumption of this medication, patients should get informed about potential adverse effects to be able to determine whether a newly-developed symptom is a sign of a health issue or just a side effect associated with Phentermine. Some brands use a dissolving tablet that is placed under the tongue, which allows the body to absorb the chemicals in the drug faster. Along with Ohio's telehealth law in Sub. After the tablet has melted, swallow or take a sip of water. Concomitant use of alcohol with phentermine may result in an adverse drug reaction. Tak YJ, et al. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. A single copy of these materials may be reprinted for noncommercial personal use only. the unsubscribe link in the e-mail. Package insert / product label These are two schedule- IV medications, phentermine/topiramate (Qsymia), and locaserin (Belviq), as well as non-controlled naltrexone hydrochloride/ buproprion hydrochloride (Contrave). Doctors often prescribe a dose of 5-HTP and vitamin B12 with a Phentermine prescription in order to enhance its effects and to relieve some side effects. Children 15 years of age and youngerUse is not recommended. Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. The drug has two primary functions in the human body, which is the reason why it is always accompanied by these lifestyle changes. However, phentermine is not appropriate or safe for everyone. Want to get more tips, information, and motivation? If the drug is taken too late in the day, it may also cause insomnia. Phentermine Hydrochloride Tablets are indicated only as short-term (a few weeks) monotherapy for the management of exogenous obesity. While the drug is considered to be relatively safe for individuals who are older than 16, the recommended age is 18. Specializes in Cardiology, Research, Family Practice. In fact, one study conducted at the Duke University School of Medicine found that apart from the Phentermines ability to effectively reduce body weight, it can also help improve a patients health-related quality of life. The first use of Phentermine as a drug to help treat obesity dates back to 1938. The recommended maximum dosage of Phentermine is 15 mg daily for patients with severe renal impairment (eGFR 15 to 29 mL/min/1.73m2). Burguera B, et al. Cumulative urinary excretion of Phentermine under uncontrolled urinary pH conditions was 62% to 85%. It is obvious that these symptoms can make the entire program useless. The goal of the drug is to help patients lose weight and increase energy since the withdrawal symptoms of include fatigue and weight gain through an increase in appetite, the product is rendered a waste of the patients time and money. If your dose is different, do not change it unless your doctor tells you to do so. privacy practices. iQJG\If6CuoG^|&qXegM,+vmC [To w{`F@kMxVBrH7.1g B;H _BfHPXK#Q For more information, the rule package submitted to the Common Sense Initiative (CSI) office for review can be found here:https://med.ohio.gov/LinkClick.aspx?fileticket=Q2JmI7o-3HI%3d&portalid=0, 2023 The Ohio State Medical Association. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. ]c,'303:20/) @d` )2 Phentermine is related chemically and pharmacologically to amphetamine (d- and dll-amphetamine) and other related stimulant drugs have been extensively abused. Tablets: 37.5 mg phentermine hydrochloride, USP (equivalent to 30 mg phentermine base). More specifically, this medication is an option for people with a body mass index (BMI): Weight-related conditions that may qualify a lower-BMI patient for phentermine include: type 2 diabetes, high cholesterol (hyperlipidemia), and controlled high blood pressure (hypertension) ( With respect to the care and treatment of patients with obesity, APRNs are required to incorporate the State Medical Board rules applicable to physicians and prescribing practices. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ADIPEX-P safely and effectively. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Rule 4731-11-02 | General provisions. Start with your primary care doctor and schedule an appointment to discuss weight. The doctor also looks at the patients medical history for any pre-existing medical conditions that the medication should not be taken with. A weight loss doctor will be more familiar with the research on phentermine for weight loss and, in many cases, more likely to prescribe it. Phentermine also has many potential drug interactions (e.g., with MAOIs), so the prescribing doctor and pharmacist know about ALL other medications and supplements taken within the last two weeks. BMI is calculated by taking the patients weight, in kilograms (kg), divided by the patients height, in meters (m), squared. 0 N;d0)zQ|,]8EtXy(En"GX omjU3Y3>kfkYHYi]-zhm{= o`i$G1BK%?9Z+(dm`mKt,?;6K@Q 7}}*Tw>7BkKsJ;E|Viexb T-3j%5QB%wI5'$5oB :h*C"Q7yjTzLO%6QS/u>HX 4DGz*A!1*p"7$-joX2YF8ht@\l[&LS$FU=udM&y.l_ HVMs8WQl eLg*&{dd $_;lm |NggK6,M]gu\.BNB. Doctors often combined the use of Phentermine with diuretics, thyroid hormone medicines and digitalis. You may opt-out of email communications at any time by clicking on What You Should Know Before Taking Phentermine, Frequently Asked Questions About Phentermine, refer to our phentermine drug interactions data, Frequently Asked Questions about phentermine, https://www.drugs.com/ingredient/phentermine.html, http://www.rxlist.com/adipex-p-drug/patient-avoid-while-taking.htm, http://www.everydayhealth.com/drugs/phentermine, https://www.ncbi.nlm.nih.gov/pubmed/27664021, https://www.ncbi.nlm.nih.gov/pubmed/26584649, https://www.ncbi.nlm.nih.gov/pubmed/26446094, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560177/, https://www.ncbi.nlm.nih.gov/pubmed/25911503, Feeling like they are going to faint, often accompanied by chest pain, Fluttering in the patients chest, as well as pounding heartbeats. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Phentermine has pharmacologic activity similar to amphetamine (d- and dll-amphetamine) [see Clinical Pharmacology (12.1)]. The following adverse reactions are described, or described in greater detail, in other sections: The following adverse reactions to Phentermine have been identified: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease, palpitation, tachycardia, elevation of blood pressure, ischemic events. Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and dll-amphetamine). Keep from freezing. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. In some cases, especially when the health concern is not too serious, the doctor may prescribe the drug at lower doses spread throughout the day, instead of advising the patient to take one single dose every day. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. Phentermine is for people with obesity or overweight who haven't been able to lose enough weight with diet and exercise alone to improve their health. Learn about the most popular weight loss medications. eG)mW`Bq:qq_W#!]WD w">=qtP"&Lb1=D.$MaK'5c'c84@i6j8H:{V6K}sTL N[v})xukk\+3+A{g$q5|zX99{c]Y7l3.dD6[\ U,r ,!,'\N "(%7M$7M_@3&riT~H!IJx$"SC4DiivT69SjH$2 oQ+#?G2 %Jj\ongTRQr$$Ym&" %e"[6X)X\R phIl;ZL#ac The drug is mainly an appetite suppressant, thus making a patient feel fuller after (and between) meals and making the patient more likely to consume foods that have lower amounts of calories. Broad St., 3 rd Floor GUIDANCE DOCUMENT: Physician Assistant Prescriptive Authority Effective 10/15/15 The following information is provided as guidance, and may not reference all statutes and rules Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The usual duration of treatment is 12 weeks or less. Ideally, patients should take it on an empty stomach. Some patients experience an increase in sexual interest, while others notice that they have a lower libido. There is a problem with allnurses, LLC, 175 Pearl St Ste 355, Brooklyn NY 11201 ). other information we have about you. Phentermine, an amphetamine congener, is the most widely used anti-obesity drug in the U.S. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. U.S. Food and Drug Administration. Based on Ohio's opioid prescribing guidelines, we developed an opioid prescribing rule that applies to all BWC-certified prescribers. Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Metabolism Phentermine has two metabolic pathways; hydroxylation and oxidation. Advertising revenue supports our not-for-profit mission. It is an appetite suppressant with the added ability to help the body produce more energy from fat cells. The final option is online doctors who prescribe phentermine. endstream endobj 105 0 obj <> endobj 106 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Rotate 0/Type/Page>> endobj 107 0 obj <>stream other information we have about you. The most common side effects that patients experience include tremors, headaches, dizziness, dry mouth, diarrhea, constipation, upset stomach, feeling restless and being hyperactive. Some of these include: As with many other prescription drugs, Phentermine can also interact with certain medications. However in the presence of topiramate, Phentermine Cmax and AUC increase 13% and 42%, respectively. Since 1997, allnurses is trusted by nurses around the globe. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Advise pregnant women and nursing mothers not to use Phentermine [see Use in Specific Populations (8.1, 8.3)]. United States of America, Drug Enforcement Administration, Federal Register. ADIPEX-P (phentermine hydrochloride) tablets, for oral use CIV ADIPEX-P (phentermine hydrochloride) capsules, for oral use CIV Initial U.S. Approval: 1959 Dosage should be individualized to obtain an adequate response with the lowest effective dose. Or it can help you feel full longer. In some cases, patients have also found that Phentermine interacts with drugs that contain Tranylcypromine, Henelzine, Isocarboxazid, Diethylpropion, Phendimetrazine, Amphetamine, and Benzphetamine.